| SELECTED PUBLICATIONS |
Kevin D Foust, Xueyong Wang, Vicki L McGovern, Lyndsey Braun, Adam K Bevan, Amanda M Haidet, Thanh T Le, Pablo R Morales, Mark M Rich, Arthur H M Burghes, & Brian K Kaspar. Rescue of spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN. Nature Biotech 2010; 28(3):271-4 PubMed ID: 20190738 |
| Rodino-Klapac LR, Montgomery CL, Bremer WG, Shontz KM, Malik V, Davis N, Sprinkle S, Campbell KJ, Sahenk Z, Clark KR, Walker CM, Mendell Jr, Chicoine LG. Persistent expression of FLAG-tagged micro dystrophin in nonhuman primates following intramuscular and vascular delivery. Mol Ther. 2010 Jan .18(1): 109017 Epub 2009 Nov 10 PubMed ID: 19904237 |
| Inimary T Toby, Louis G Chicoine, Hongmei Cui, Bernadette Chen, Leif D Nelin. Hypoxia-induced proliferation of human pulmonary Microvascular endothelial cells depends on epidermal growth factor receptor tyrosine kinase activation. Am J Physiol Lung Cell Mol Physiol. 2010 Apr; 298(4):L600-6. Epub 2010 Feb 5. PubMed ID: 20139181 |
| Jin Y, Calvert TJ, Chen B, Chicoine LG, Joshi MS, Bauer JA, Liu Y, Nelin LD. Mice deficient in Mkp-1 develop more severe pulmonary hypertension and greater lung protein levels of arginase in response to chronic hypoxia". Am J Physiol Heart Circ Physiol 2010 Feb 19. (Epub ahead of print) PubMed ID: 20173047 |
| Louise R Rodino-Klapac, Chrystal L Montgomery, William G Bremer, Vinrod Malik, Kimberly M Shontz, Nancy Davis, Spencer Sprinkle, Katherine J Campbell, Zarife Sahenk, K Reed Clark, Christopher M Walker, Jerry R Mendell, Louis G Chicoine. Persistent expression of FLAG tagged micro-dystrophin in non-human primates following intramuscular and vascular delivery. Mol Ther. 2010 Jan;18(1):109-17. Epub 2009 Nov 10 PubMed ID: 19904237 |
| Malik V, Rodino-Klapac LR, Viollet L, Wall C, King W, Al-Dahhak R, Lewis S, Shilling CJ, Kota J, Serrano-Munuera C, Hayes J, Mahan JD, Campbell KJ, Banwell B, Dasouki M, Watts V, Sivakumar K, Bien-Willner R, Flanigan KM, Sahenk Z, Barohn RJ, Walker CM, Mendell JR. Gentamicin-induced readthrough of stop condons in duchenne muscular dystrophy. PubMed ID: 20517938 |
| Mendell Jr, Rodino-Klapac LR, Malik V. Molecular Therapeutic Strategies Targeting Muscular Dystrophy. J Child Neurol. 2010 May 24 (Epub ahead of print) PubMed ID: 20498331 |
| Rodino-Klapac LR, Montgomery CL, Bremer WG, Shontz KM, Malik V, Davis N, Sprinkle S, Campbell KJ, Sahenk Z, Clark KR, Walker CM, Mendell JR, Chicoine LG.Persistent expression of FLAG-tagged micro dystrophin in nonhuman primates following intramuscular and vascular delivery.Mol Ther. 2010;18(1):109-17. PubMed ID: 19904237 |
| Rodino-Klapac LR, Montgomery CL, Bremer WG, Shontz KM, Malik V, Davis N, Sprinkle S, Campbell KJ, Sahenk Z, Clark KR, Walker CM, Mendell JR, Chicoine LG. Persistent expression of FLAG-tagged micro dystrophin in nonhuman primates following intramuscular and vascular delivery. Mol Ther. 2010 Jan;18(1):109-17. PubMed ID: 19904237 |
| Saechao C, Valles-Ayoub Y, Esfandiarifard S, Haghighatgoo A, No D, Shook S, Mendell JR, Rosales-Quintero X, Felice KJ, Morel CF, Pietruska M, Darvish D.Novel GNE Mutations in Hereditary Inclusion Body Myopathy Patients of Non-Middle Eastern Descent. Genet Test Mol Biomarkers. 2010 Jan 10 . |
| Stenger M, Rose M, Joshi M, Rogers L, Chicoine LG, Welty S, Bauer J, Nelin LD, Inhaled Nitric Oxide Prevents 3-nitrotyrosine Formation in the Lungs of Neonatal Mice Exposed to Lethal Hyperoxia. Am J Physiol Lung Cell Mol Physiol. 2010 Mar 17. PubMed ID: 20237791 |
Flanigan, K. M., D. M. Dunn, A. von Niederhausern, P. Soltanzadeh, E. Gappmaier, M. T. Howard, J. B. Sampson, J. R. Mendell, C. Wall, W. M. King, A. Pestronk, J. M. Florence, A. M. Connolly, K. D. Mathews, C. M. Stephan, K. S. Laubenthal, B. L. Wong, P. J. Morehart, A. Meyer, 2009. Mutational spectrum of DMD mutations in dystrophinopathy patients: application of modern diagnostic techniques to a large cohort. Hum Mutat 30:1657-66. PubMed ID: 19937601 |
Flanigan, K. M., D. M. Dunn, A. von Niederhausern, M. T. Howard, J. Mendell, A. Connolly, C. Saunders, A. Modrcin, M. Dasouki, G. P. Comi, R. Del Bo, A. Pickart, R. Jacobson, R. Finkel, L. Medne, and R. B. Weiss. 2009. DMD Trp3X nonsense mutation associated with a founder effect in North American families with mild Becker muscular dystrophy. Neuromuscul Disord 19:743-8. PubMed ID: 19793655 |
Johnson, P. R., B. C. Schnepp, J. Zhang, M. J. Connell, S. M. Greene, E. Yuste, R. C. Desrosiers, and K. R. Clark. 2009. Vector-mediated gene transfer engenders long-lived neutralizing activity and protection against SIV infection in monkeys. Nat Med 15:901-6. PubMed ID: 19448633 |
Kota, J., R. R. Chivukula, K. A. O'Donnell, E. A. Wentzel, C. L. Montgomery, H. W. Hwang, T. C. Chang, P. Vivekanandan, M. Torbenson, K. R. Clark, J. R. Mendell, and J. T. Mendell. 2009. Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell 137:1005-17. PubMed ID: 19524505 |
Martin, P. T., R. Xu, L. R. Rodino-Klapac, E. Oglesbay, M. Camboni, C. L. Montgomery, K. Shontz, L. G. Chicoine, K. R. Clark, Z. Sahenk, J. R. Mendell, and P. M. Janssen. 2009. Overexpression of Galgt2 in skeletal muscle prevents injury resulting from eccentric contractions in both mdx and wild-type mice. Am J Physiol Cell Physiol 296:C476-88. PubMed ID: 19109526 |
Mendell, J. R., L. R. Rodino-Klapac, X. Rosales-Quintero, J. Kota, B. D. Coley, G. Galloway, J. M. Craenen, S. Lewis, V. Malik, C. Shilling, B. J. Byrne, T. Conlon, K. J. Campbell, W. G. Bremer, L. Viollet, C. M. Walker, Z. Sahenk, and K. R. Clark. 2009. Limb-girdle muscular dystrophy type 2D gene therapy restores alpha-sarcoglycan and associated proteins. Ann Neurol 66:290-7. PubMed ID: 19798725 |
Rodino-Klapac, L. R., C. L. Montgomery, W. G. Bremer, K. M. Shontz, V. Malik, N. Davis, S. Sprinkle, K. J. Campbell, Z. Sahenk, K. R. Clark, C. M. Walker, J. R. Mendell, and L. G. Chicoine. 2009. Persistent Expression of FLAG-tagged Micro dystrophin in Nonhuman Primates Following Intramuscular and Vascular Delivery. Mol Ther. PubMed ID: 19904237 |
Schnepp, B. C., R. L. Jensen, K. R. Clark, and P. R. Johnson. 2009. Infectious molecular clones of adeno-associated virus isolated directly from human tissues. J Virol 83:1456-64.
PubMed ID: 19019948 |
Butterfield, R. J., D. Ramachandran, S. J. Hasstedt, B. E. Otterud, M. F. Leppert, K. J. Swoboda, and K. M. Flanigan. 2009. A novel form of juvenile recessive ALS maps to loci on 6p25 and 21q22. Neuromuscul Disord 19:279-87. PubMed ID: 19318250 |
Gurvich, O. L., B. Maiti, R. B. Weiss, G. Aggarwal, M. T. Howard, and K. M. Flanigan. 2009. DMD exon 1 truncating point mutations: amelioration of phenotype by alternative translation initiation in exon 6. Hum Mutat 30:633-40. PubMed ID: 19206170 |
Maiti, B., S. Arbogast, V. Allamand, M. W. Moyle, C. B. Anderson, P. Richard, P. Guicheney, A. Ferreiro, K. M. Flanigan, and M. T. Howard. 2009. A mutation in the SEPN1 selenocysteine redefinition element (SRE) reduces selenocysteine incorporation and leads to SEPN1-related myopathy. Hum Mutat 30:411-6. PubMed ID: 19067361 |
Excoffon KJ, Koerber JT, Dickey DD, Murtha M, Keshavjee S, Kaspar BK, Zabner J, Schaffer DV. Directed evolution of adeno-associated virus to an infectious respiratory virus. Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3865-70 PubMed ID: 19237554 |
Hester M, Song SW, Miranda C, Eagle A, Schwartz P, Kaspar BK. Two Factor Reprogramming of Human Neural Stem Cells into Pluripotency, PLoS One. 2009, 4(9):e7044. PubMed ID: 19763260 |
Hester ME, Foust KD, Kaspar RW, Kaspar BK. AAV as a gene transfer vector for the treatment of neurological disorders: novel treatment thoughts for ALS. Curr Gene Ther. 2009 Oct;9(5):428-33. PubMed ID: 19860657 |
Janaiah Kota, Chalonda R. Handy, Amanda M. Haidet, Chrystal L. Montgomery, Amy Eagle, Louise R. Rodino-Klapac, Danielle Tucker, Christopher J. Shilling, Walter R. Therlfall, Christopher M. Walker, Steven E. Weisbrode, Paul M. L. Janssen, K. Reed Clark, Zarife Sahenk, Jerry R. Mendell, Brian K. Kaspar. Follistatin Gene Delivery Enhances Muscle Growth and Strength in nonhuman primates. Science Translational Medicine, 2009 Nov 11;1(6) 6ra15 PubMed ID: 20368179 |
Kaspar RW, Wills CE, Kaspar BK. Gene therapy and informed consent decision making: nursing research directions. Biol Res Nurs. 2009 July;11(1):98-107. PubMed ID: 19398415 |
Kevin D. Foust and Brian K. Kaspar. Over the barrier and through the blood To CNS delivery we go. Cell Cycle. 2009 8(24)16-17 PubMed ID: 19949299 |
Mendell JR, Rodino-Klapac LR, Rosales-Quintero X, Kota J, Coley BD, Galloway G, Craene JM, Lewis S, Malik V, Shilling C, Byrne BJ, Conlon T, Campbell KJ, Bremer WG, Violiet L, Walker CM, Sahenk Z, Clark KR. Limb-girdle muscular dystrophy type 2D gene therapy restores alpha-sarcoglycan and associated proteins. Ann Nerol. 2009 Sept;666(3):290-7 PubMed ID: 1979725 |
Rodino-Klapac LR, Haidet AM, Kota J, Handy C, Kaspar BK, Mendell JR. Inhibition of myostatin with emphasis on follistatin as a therapy for muscle disease. Muscle Nerve. 2009 Mar;39(3):283-296. PubMed ID: 19208403 |
| Clark, K. R., and S. T. Walsh Dec 2009, posting date. Crystal structure of a 3B3 variant--a broadly neutralizing HIV-1 scFv antibody 2009/09/29. PubMed ID: 19785005 |
| Chicoine LG, Steward JA, Lucchesi, PA. Is Resveratrol the Magic Bullet for Pulmonary Hypertension? Hypertension 2009 Sept; 54(3): 473-4. Epub July 13. PubMed ID: 19597034 |
| Mendell JR, Rodino-Klapac LR, Rosales-Quintero X, Kota J, Coley BD, Galloway G, Craenen JM, Lewis S, Malik V, Shilling C, Byrne BJ, Conlon T, Campbell KJ, Bremer WG, Viollet L, Walker CM, Sahenk Z, Clark KR.Limb-girdle muscular dystrophy type 2D gene therapy restores alpha-sarcoglycan and associated proteins. Ann Neurol. 2009 Sep;66(3):290-7. PubMed ID: 19798725 |
| Montanaro F. and Martin, P.T. (2009). Defective glycosylation of dystroglycan in muscular dystrophy and cancer. In “Post-translational Modifications in Health and Disease”. Editor Cecilio Vidal Moreno. Protein Reviews Series. Series Editor Zouhair Atassi, M., in press. |
| Rodino-Klapac LR, Haidet AM, Kota J, Handy C, Kaspar BK, Mendell JR. Inhibition of myostatin with emphasis on follistatin as a therapy for muscle disease. Muscle Nerv. 2009 Mar;39(3):283-96. Review. PubMed ID: 19208403 |
| Elsheikh B, Kissel JT, Christoforidis G, Wicklund M, Kehagias DT, Chiocca EA, Mendell JR. Spinal angiography and epidural venography in juvenile muscular atrophy of the distal arm "Hirayama disease". Muscle Nerve. 2009 Aug;40(2):206-12.PMID: 19609908 PubMed ID: 19609908 |
| Elsheikh B, Prior T, Zhang X, Miller R, Kolb SJ, Moore D, Bradley W, Barohn R, Bryan W, Gelinas D, Iannaccone S, Leshner R, Mendell JR, Mendoza M, Russman B, Smith S, King W, Kissel JT. An analysis of disease severity based on SMN2 copy number in adults with spinal muscular atrophy. Muscle Nerve. 2009 Oct;40(4):652-6. PubMed ID: 19760790 |
| Flanigan KM, Dunn DM, von Niederhausern A, Soltanzadeh P, Gappmaier E, Howard MT, Sampson JB, Mendell JR, Wall C, King WM, Pestronk A, Florence JM, Connolly AM, Mathews KD, Stephan CM, Laubenthal KS, Wong BL, Morehart PJ, Meyer A, Finkel RS, Bonnemann CG, Medne L, Day JW, Dalton JC, Margolis MK, Hinton VJ; United Dystrophinopathy Project Consortium, Weiss RB.Mutational spectrum of DMD mutations in dystrophinopathy patients: application of modern diagnostic techniques to a large cohort. Hum Mutat. 2009 Dec;30(12):1657-66. PubMed ID: 19937601 |
| Foust KD, Nurre E, Montgomery CL, Hernandez A, Chan CM, Kaspar BK. Intravascular AAV9 preferentially targets neonatal neurons and adult astrocytes. Nat Biotechnol. 2009 Jan;27(1):59-65 PubMed ID: 19098898 |
| Guenther UP, Handoko L, Varon R, Stephani U, Tsao CY, Mendell JR, Lützkendorf S, Hübner C, von Au K, Jablonka S, Dittmar G, Heinemann U, Schuetz A, Schuelke M.Clinical variability in distal spinal muscular atrophy type 1 (DSMA1): determination of steady-state IGHMBP2 protein levels in five patients with infantile and juvenile disease. J Mol Med. 2009 Jan;87(1):31-41. PubMed ID: 18802676 |
| Hilario JD, Rodino-Klapac LR, Vvang C, Beattie CE. Semaphorin 5A is a bifunctional axon guidance cue for axial motoneurons in vivo. Dev Biiol. 2009 Feb 1;326(1): 190-200. Epub 2008 Nov 20 PubMed ID: 19059233 |
| Kaspar RW, Allen HD, Ray WC, Alvarez CE, Kissel JT, Pestronk A, Weiss RB, Flanigan KM, Mendell JR, Montanaro F. Analysis of dystrophin deletion mutations predicts age of cardiomyopathy onset in becker muscular dystrophy. Circ Cardiovasc Genet. 2009 Dec;2(6):544-51. PubMed ID: 20031633 |
| Kaspar, R.W., Allen, H.D. and Montanaro F. (2009). Current understanding and management for dilated cardiomyopathy in Duchenne and Becker muscular dystrophy. Journal of the American Academy of Nurse Practitioners,21(5):241-9 PubMed ID: 19432907 |
| Kota J, Chivukula RR, O'Donnell KA, Wentzel EA, Montgomery CL, Hwang HW, Chang TC, Vivekanandan P, Torbenson M, Clark KR, Mendell JR, Mendell JT. Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell. 2009 Jun 12;137(6):1005-17. PubMed ID: 19524505 |
| Kota J, Handy CR, Haidet AM, Montgomery CL, Eagle A, Rodino-Klapac LR, Tucker D, Shilling CJ, Therlfall WR, Walker CM, Weisbrode SE, Janssen PM, Clark KR, Sahenk Z, Mendell JR, Kaspar BK. Follistatin gene delivery enhances muscle growth and strength in nonhuman primates.Sci Transl Med.2009;1(6):6ra15. PubMed ID: 20368179 |
| Kota J. Handy CR, Haidet AM, Montgomery CL, Eagle A, Rodino-Klapac LR, Tucker D, Shilling CJ, Therifall WR, Walker CM, Weisbrode SE, Janssen PM, Clark KR, Sahenk Z, Mendell Jr, Kaspar BK. Follistatin gene delivery enhances muscle growth and strength in nonhuman primates. Sci Trans! Med. 2009 Nov 11:(6): 6ra15. PubMed ID: 20368179 |
| Martin PT, Xu R, Rodino-Klapac LR, Oglesbay E, Camboni M, Montgomery CL, Shontz K, Chicoine LG, Clark KR, Sahenk Z, Mendell Jr, Janssen PM. Overexpression of Galgt2 in skeletal muscle prevents injury resulting from eccentric contractions in both mdx and wild-type mice. Am J Physiol Cell Physioi. 2009 Mar;296(3):C476-88. Epub 2008 Dec 24 PubMed ID: 19109526 |
| Martin PT, Xu R, Rodino-Klapac LR, Oglesbay E, Camboni M, Montgomery CL, Shontz K, Chicoine L, Clark KR, Sahenk Z, Mendell JR, Janssen PM. Overexpression of Galgt2 in skeletal muscle prevents injury resulting from eccentric contractions in both mdx and wild type mice. Am J Physiol Cell Physiol. 2009 Mar;296(3): C476-88. Epub 2008 Dec 24. PubMed ID: 19109526 |
| Martin PT, Xu R, Rodino-Klapac LR, Oglesbay E, Camboni M, Montgomery CL, Shontz K, Chicoine LG, Clark KR, Sahenk Z, Mendell JR, Janssen PM. Overexpression of Galgt2 in skeletal muscle prevents injury resulting from eccentric contractions in both mdx and wild-type mice.Am J Physiol Cell Physiol. 2009;296(3):C476-88. PubMed ID: 19109526 |
| Martin PT, Xu R, Rodino-Klapac LR, Oglesbay E, Camboni M, Montgomery CL, Shontz K, Chicoine LG, Clark KR, Sahenk Z, Mendell JR, Janssen PM.Overexpression of Galgt2 in skeletal muscle prevents injury resulting from eccentric contractions in both mdx and wild-type mice. Am J Physiol Cell Physiol. 2009 Mar;296(3):C476-88. PubMed ID: 19109526 |
| Mendell JR, Rodino-Klapac LR, Rosales-Quintero X, Kota J, Coley BD, Galloway G, Craenen JM, Lewis S, Malik V, Shilling C, Byrne BJ, Conlon T, Campbell KJ, Bremer WG, Viollet L, Walker CM, Sahenk Z, Clark KR. Limb-girdle muscular dystrophy type 2D gene therapy restores alpha-sarcoglycan and associated proteins.Ann Neurol. 2009;66(3):290-7. PubMed ID: 19798725 |
| Rodino-Klapac LR, Haidet AM, Kota J, Handy C, Kaspar BK, Mendell JR. Inhibition of myostatin with emphasis on follistatin as a therapy for muscle disease. Muscle Nerve. 2009 Mar;39(3):283-96. Review. PubMed ID: 19208403 |
| S.Q. Harper. Progress and challenges in RNAi therapy for Huntington's Disease. Arch Neurol. 2009 Aug;66(8):933-8. Review. Erratum in: Arch Neurol. 2009 Oct;66(10):1272. PubMed ID: 19667213 |
| Thrush PT, Allen HD, Viollet L, Mendell JR. Re-examination of the electrocardiogram in boys with Duchenne muscular dystrophy and correlation with its dilated cardiomyopathy. Am J Cardiol. 2009 Jan 15;103(2):262-5. PubMed ID: 19121448 |
| Tsao CY, Mendell JR. Partial epilepsy in an adolescent male with limb-girdle muscular dystrophy 1B. J Child Neurol. 2009 Mar;24(3):346-8. PubMed ID: 19258295 |
| Viollet L, Gailey S, Thornton DJ, Friedman NR, Flanigan KM, Mahan JD, Mendell JR. Utility of cystatin C to monitor renal function in Duchenne muscular dystrophy. Muscle Nerve. 2009 Sep;40(3):438-42. PubMed ID: 19623638 |
Gurvich, O.L., Tuohy, T.M., Howard, M.T., Finkel, R.S., Medne, L., Anderson, C.B., Weiss, R.B., Wilton, S.D., Flanigan, K.M. (2008) DMD pseudoexon mutations: splicing efficiency, phenotype, and potential therapy. Ann Neurol., 2008 Jan;63(1):81-9. PubMed ID: 18059005 |
Haidet AM, Rizo L, Handy C, Umapathi P, Eagle A, Shilling C, Boue D, Martin PT, Sahenk Z, Mendell JR, Kaspar BK. Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors. Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4318-22. PubMed ID: 18334646 |
J.L. McBride*, R.L. Boudreau*, S.Q. Harper* (shared first authorship), A. Mas Monteys, P.D. Staber, I. Martins, B. Gilmore, H. Burstein, R.W. Peluso, B. Polisky, B.J. Carter, and B.L. Davidson. MicroRNA shuttles mitigate short-hairpin RNA mediated toxicity in the brain: Implications for therapeutic development of RNA interference. (2008) Proceedings of the National Academy of Sciences, USA 105(15): 5868-73. PubMed ID: 18398004 |
McCrate ME, Kaspar BK. Physical activity and neuroprotection in amyotrophic lateral sclerosis. Neuromolecular Med. 2008;10(2):108-17. PubMed ID: 18286388 |
Miller TM, Smith RA, Kordasiewicz H, Kaspar BK. Gene-targeted therapies for the central nervous system. Arch Neurol. 2008 Apr;65(4):447-51. Epub 2008 Feb 11 PubMed ID: 18268183 |
Zhang X, CY, Sahenk Z, Shy ME, Meisler MH, Li J. Mutation of FIG4 causes a rapidly progressive, asymmetric neronal degenernation. Brain 2008;131(Pt8):1990-2001 PubMed ID: 18556664 |
| Brian K Kaspar. Mesenchymal Stem Cells as Trojan Horses for GDNF Delivery in ALS. Molecular Therapy, Vol. 16(12):2008. PubMed ID: 19032270 |
| Rodino-Klapac LR, Lee JS, Mulligan RC, Clark KR, Mendell JR. Lack of toxicity of alpha-sarcoglycan overexpression supports clinical gene transfer trial in LGMD2D. Neurology. 2008 Jul 22;7(4):240-7. Epub 2008 Jun 4. PubMed ID: 18525034 |
| Sahenk Z, Oblinger J, Edwards C. Neurotrophin-3 deficient Schwann cells impair nerve regeneration. Exp Neurol. 2008 Aug;212(2):552-556. PubMed ID: 18511043 |
| A. Packer, Y. Xing, S.Q. Harper, L. Jones, and B.L. Davidson. The bi-functional microRNA mir9/mir9* regulates REST and coREST and is down-regulated in Huntington's desease (2008) Journal of Neuroscience, 28(53):14341-6 PubMed ID: 19118166 |
| Calvert TJ, Chicoine LG, Liu Y, Nelin LD. Deficiency of Mitogen Activated Protein Kinase Phosphatase-1 Results in iNOS-mediated Hypotension in Response to Low-Dose Endotoxin. Am J Physiol Heart Circ Physiol. 2008 Apr; 294(4): H1621-9 Epub 2008 Feb 15 PubMed ID: 182813281 |
| Chang, R, Chicoine LG, CuiH, Kanagy NL, Walker BR, Liu Y, English BK, Nelin LD. Cytokine-induced Arginase Activity in Pulmonary Endothelial Cells is Dependent on Src-Family Tyrosine Kinase Activity. Am J Physiol Lung Cell Mol Physiol . 2008 Oct;295(4):L688-L697. Epub 2008 Jul 11. PMID: 18621907 PubMed ID: 18621907 |
| Haidet AM, Rizo L, Handy C, Umapathi P, Mendell JR, Kaspar BK, et. al. Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitors. Proc Natl Acad Sci U S A. 2008 Mar 18;105(11):4318-22. PubMed ID: 18334646 |
| Kannanayakal TJ, Mendell JR, Kuret J. Casein kinase 1 alpha associates with the tau-bearing lesions of inclusion body myositis. Neurosci Lett. 2008 Jan 31;431(2):141-5. PubMed ID: 18191026 |
| Kim ML, Chandrasekharan K, Glass M, Shi S, Stahl MC, Kaspar B, Stanley P, Martin PT. O-funocylation of muscle agrin determines its ability to cluster acetylcholine receptors, Mol Cell Neurosci, 2008 Nov;39(3):452-64 PubMed ID: 18775496 |
| Rodino-Klapac LR, Lee J-S, Mulligan RC, Clark KR, Mendell JR. Lack of toxicity of alpha-sarcoglycan overexpression supports clinical gene transfer in LGMD2D. Neurology 2008 Jul 22;71(4):240-7. PubMed ID: 18525034 |
| Rosales XQ, Shilling C, Wall C, Chu M-L, Mendell JR. Fidelity of Serum Gamma-glutamyl transferase in differentiating skeletalmuscle from liver disease in Duchenne muscular dystrophy. J Child Neurol. 2008 Jul;23(7):748-51. PubMed ID: 18354148 |
| S.Q. Harper and Gonzalez-Alegre P. Lentivirus-mediated RNA interference in mammalian neurons. (2008) Methods in Molecular Biology 442, 95-112. PubMed ID: 18369781 |
| Tsao CY, Mendell J, Sahenk Z, Rusin J, Boue D. Hypotonia, weakness, and pontocerebellar hypoplasia in siblings. Semin Pediatr Neurol. 2008;15(4):151-3. PubMed ID: 19073313 |
| Wagner KR, Fleckenstein JL, Amato AA, Barohn RJ, Mendell JR et al. A phase I/IItrial of MYO-029 in adult subjects with muscular dystrophy. Ann Neurol. 2008 May;63(5):561-71. PubMed ID: 18335515 |
Rodino-Klapac L, Chicoine L, Kaspar B, Mendell JR. Gene Therapy for Duchenne Muscular Dystrophy: Expectations and Challenges. Arch Neurol. 2007 Sep;64(9):1236-41. PubMed ID: 17846262 |
King WM, Ruttencutter R, Nagaraja HN, Matkovic V, Landoll J, Hoyle C, Mendell JR, Kissel JT. Orthopedic outcomes of long-term daily corticosteroid treatment in Duchenne muscular dystrophy. Neurology. 2007 May 8;68(19):1607-13. PubMed ID: 17485648 |
Rodino-Klapac L, Janssen PML, Montgomery CL, Coley BD, Chicoine LG, Clark KR, Mendell JR. A Translational Approach for Limb Vascular Delivery of the Micro-dystrophin Gene without High Volume or High Pressure for Treatment of Duchenne Muscular Dystrophy. J Transl Med. 2007 Sep 24;5:45. PubMed ID: 17892583 |
Rodino-Klapac LR, Janssen PM, Comtgomery CL, Coley BD, Chicoine LG, Clark KR, Mendell JR. A translational approach for limb vascular delivery of the micro-dystrophin gene without high volume or high pressure for treatment of Duchenne muscular dystrophy. J Transl Med. 2007 Sept 24;5:45 PubMed ID: 18525034 |
Rodino-Klapac LR, Chicoine LG, Kaspar BK, Mendell JR. Gene therapy for duchenne muscular dystrophy: expectations and challenges. Arch Neurol. 2007 Sep;64(9):1236-41. PubMed ID: 17846262 |
Xu, R, Camboni, M., Martin, P.T., Postnatal overexpression of the CT GalNAc transferase inhibits muscular dystrophy in mdx mice without altering muscle growth or neuromuscular development: Evidence for a utrophin-independent mechanism. Neuromuscul Disord. 2007 Feb. 12; [Epub ahead of print] PubMed ID: 17300937 |
| Chicoine LG, Paffett ML, Girton MR, Metropoulus MJ, Joshi MS, Bauer JA, Nelin LD, Resta TC, Walerk BR. Am J Physiol Lung Cell Mol Physiol. 2007 Nov;293(5):L1261-70. Epub 2007 Sep.7 PubMed ID: 17827249 |
| Fu, H., Kang, L., Jennings, J.S., Moy, S.S., Perez, A., DiRosario, J., McCarty, D.M., Muenzer, J., Significantly increased lifespan and improved behavioral performances by rAAV gene delivery in adult Mucopolysaccharidosis IIIB mice. Gene Therapy, 2007 Apr 26; [Epub ahead of print] PubMed ID: 17460717 |
| Louise R Rodino-Klapac, Paul ML Janssen, Chrystal L Montgomery, Brian D Coley, Louis G Chicoine, K Reed Clark, and Jerry R Mendell. A translational approach for limb vascular delivery of the micro-dystrophin gene without high volume or high pressure for treatment of Duchenne muscular dystrophy. Journal of Translational Medicine 2007, 5:45 PubMed ID: 17892583 |
| Nankervis CA, Preston TJ, Dysart KC, Wilkinson WD, Chicoine LG, Welty SE, Nelin LD. Assessing heparin dosing in neonates on venoarterial extracorporeal membrane oxygenation. ASAIO J. 2007 Jan-Feb;53-(1):111-4 PubMed ID: 172376558 |
| Nelin LD, Stenger MR, Malleske DT, Chicoine LG. Vascular Arginase and Hypertension. Current Hypertension Reviews. 2007 Nov;3(4):242-249. |
| Nelin Ld, Wang X, ZhaoQ, Chicoine LG, Yount TL, Hatch DM, English BK, Liu Y. MKP-1 Switches Arginine Metabolism from Nitric Oxide Synthase to Arginase following Endotoxin Challenge. 2007 Aug;293(2):C632-40. Epub 2007 Apr 18 PubMed ID: 17442735 |
| Pope AJ, Druham L, Gusman JE, Forbes SP, Murugesan V, Lu D, Xia Y, Chicoine LG, Parinandi NL, Cardounel AJ. . Role of DDAH-1 in Lipid Peroxidation Product mediated inhibition of Endothelial NO Generation. Am J Physiol Cell Physiol. 2007 Nov;293(5):C1679-86. Epub 2007 Sept 19. PubMed ID: 17881609 |
| Rodino-Klapac LR, Chicoine LG, KasparBK,Mendell JR. Gene therapy for duchenne muscular dystrophy: expectations and challenges. Arch Neurol. 2007 Sep:64(9):1236-41 PubMed ID: 17846262 |
| Martin, P.T. Congenital muscular dystrophy – Glycosylation takes center stage. Nature Clinical Practice Neurology. 2006 Apr; 2 (4) 222-230. PubMed ID: 16932553 |
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